Four flames kindled on the highest peaks of the UK come together at Stoke Mandeville, the spiritual home of the Paralympics, before the final torch relay towards east London on Wednesday.
Cauldrons have been lit in England, Northern Ireland, Scotland and Wales over the past week, and on Tuesday evening the four fires will unite at Stoke Mandeville Stadium in Buckinghamshire.
Afterwards the single flame will be taken to the National Spinal Injuries Centre where Dr Ludwig Guttmann laid the foundations for the modern Paralympic Games in July 1948 with a low key archery and javelin competition for patients.
From there, a 24-hour torch relay will take the flame to the Opening Ceremony in Stratford to mark the start of the London 2012 Paralympic Games.
The Paralympic Flame will be carried 92 miles by 580 torchbearers, working in teams of five.
The flame will travel through communities in Buckinghamshire and Hertfordshire before visiting a number of London landmarks, including Piccadilly Circus, Westminster Abbey, Downing Street and Trafalgar Square.
Inspirational people, including some nominated by Prince Harry and Lord Coe, will help carry the torch towards the Olympic Stadium in east London.
Former boxer Michael Watson, who was left with a brain injury and paralysed following a fight with Chris Eubank in 1991, will carry the torch through Trafalgar Square.
Read more: Paralympics founder Sir Ludwig Guttmann honoured
Other torchbearers include Britain’s 11-time athletics Paralympic champion Tanni Grey-Thompson, a team of PE teachers who teach Paralympic Sports and members of Chelsea FC’s pan-disability squad who will will carry the flame to Westminster Abbey.
Channel 4 News presenter Jon Snow, who will be carrying the torch for part of its journey through the City of London, said “I’m incredibly proud to be anywhere near the Paralympic endeavour, and I’ll be splashing out to buy my torch afterwards”.
Last Wednesday, four Paralympic flames were kindled at the top of the highest peaks of Northern Ireland, Wales, Scotland and England – Slieve Donard, Snowdon, Ben Nevis and Scafell Pike.